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Pharmaceuticals

WHY AND HOW WE USE NEUTRONS?

CASE STUDIES

(pdf - 705 Ki)
(pdf - 707 Ki)

"Neutrons have proven themselves to be a key resource for this project; we needed to analyse the p7 protein structure in a specific environment. Now we can take this deep understanding of the virus not only to devices like biosensors, but also to other fields, to study the behaviour of membrane proteins in lipid bilayers, for example.” Bruno Tillier, Managing Director, Synthelis

TECHNIQUES RELEVANT TO THE FIELD

PRICE EXAMPLES

Prices can vary depending on the complexity of the measurement

  • SANS data: from 150 EUR/sample
  • Identification of crystalline planes (Laue diffraction pattern): from 100 EUR/sample
  •  In-situ (temperature, pressure) diffraction data: from 6 kEUR

NEWS CORNER

Liposomes caught drunk-dancing in solution

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Protein biopharmaceuticals: understanding the processes to take applications further

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A recently published study uses neutron and X-ray scattering to deepen our understanding of freeze-drying protein stabilisation processes, widely used in biopharmaceutical applications. The results obtained for a protein relevant for pharmaceutical…

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ILL is the chosen partner of Novartis to deliver a new cancer treatment drug

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The Swiss company NOVARTIS announced at the Choose France Summit the desire to establish a partnership with the ILL, already a partner of other pharmaceutical companies for radioisotope production for cancer treatment and research. This is part of a…

Deuterated natural phospholipids for advanced cellular membrane models

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Understanding the interactions of biomolecules such as proteins or drugs with the membrane of cells is important in biomedical research and for the pharmaceutical industry. The sensitivity of neutrons to hydrogen atoms make neutron scattering a…

How hydrogels could turn the tide in the treatment of HIV

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Courtesy of Alison Oliver (STFC,RAL,ISIS)

Neutron scattering and selective deuteration reveal the structure and composition of mRNA-containing LNPs and the effects induced by the serum protein ApoE

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Anticancer drugs: new insights revealed by a powerful and complementary multi-technique approach

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Capturing carbon dioxide for the chemical industry

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The dynamics of the E. coli proteome at cell death temperature

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